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In this trasngene construct, a rat Fabp1 promoter fragment (nt -596 to +21) drives the expression of a 1103-bp a-1,3/4-fucosyltransferase human cDNA which includes a 1086-nt coding region specifying the 361-aa type II transmembrane glycoprotein, an upstream Kozak consensus sequence and HindIII site, and a downstream Not I recognition site. A founder male was used to establish a line of mice that contained three copies of the transgene per haploid genome. (J:23324)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
