Exons 5 and 6 were flanked by loxP sites and a FRT-flanked positive selection marker puromycin was inserted in intron 4. Flp-mediated recombination removed the puromycin gene. (J:247100)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count