This allele was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences CCTGCAGTGGACCTTGAACG, TAGAGCTGCCCCGAGAGCAG, CCTACGGGAGCTTATCAGGG and CATCTTGGTGAGCAGGGCAT, which resulted in a 519 bp deletion beginning at Chromosome 4 position 156,250,058 bp and ending after 156,250,576 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001049485 (exon 5) and 356 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 106 and early truncation 19 amino acids later. (J:188991)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count