Exon 1 was flanked by loxP sites and FRT-flanked neomycin cassette was inserted downstream of exon 1 before the second loxP site. Flp-mediated recombination removed the neomycin cassette. (J:232417)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count