Exon 2 was flanked by loxP sites. A FRT-flanked neomycin cassette was inserted upstream of the floxed exon 2. Flp-mediated recombination removed the neomycin cassette. (J:238687)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count