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Thetargeting vector was constructed with the cre/ERT2 gene knocked into the initiator methionine of mouse ASIC4 to replace first 267 amino acid peptides in the N-terminus of ASIC4. A pGK-neo selection cassette flanked by loxP sites was placed downstream of the polyadenylation signal of cre/ERT2. The floxed-pGK-neo cassette was removed by crossing with cre expressing mice. It is a null allele. (J:253311)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
