The targeting construct contained loxP sites flanking exon 4 and a FRT-flanked PGK-neomycin selection cassette inserted between exons 3 and 4. Flp-mediated recombination removed the neomycin cassette. (J:239395)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count