The transgene was created by modifying BAC clone RP23-395E7 by inserting an improved cre recombinase gene (icre) to replace exon 1 of mouse Grpr gene. An FRT-flanked ampicillin resistance cassette was removed prior to injection. Two lines were generated. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:247582)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count