The targeting vector inserted loxP sites flanking exon 1 and an adjacent neomycin resistance gene with another loxP site at the 3' end. The floxed neo was removed via cre-mediated recombination. (J:244504)
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The targeting vector inserted loxP sites flanking exon 1 and an adjacent neomycin resistance gene with another loxP site at the 3' end. The floxed neo was removed via cre-mediated recombination. (J:244504)