The CreERT2-pA-FRT-Neo-FRT was inserted into exon 4 of the Trp63 gene resulting in an in-frame fusion after 115th a.a. of Trp63 isoform. Male chimeric mice were crossbred with female FLPeR mice to remove to remove the Frt-flanked PGK-neo cassette. (J:249188)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count