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The targeting vector using bacterial artificial chromosomes (BACs) from the C57BL/6J RPCIB-731 BAC library was constructed by inserting a CreERT2 cassette and F3 flanked puromycin resistant cassette into the second exon of the Gfra1 gene in frame. The vector was transfected into the TaconicArtemis C57BL/6N Tac ESC line to establish mouse line by homologous recombination. Flp-mediated recombination removed the F3-flanked puro cassette. (J:251552)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
