The IKMC targeting vector PG00154_Z_5_F10 was used to insert a construct containing an FRT site, lacZ gene, loxP site, neo gene, FRT site and loxP site upstream of exon 4 and a third loxP site downstream of exon 4. Flp mediated recombination removed the lacZ and neo genes leaving exon 4 floxed. (J:256331)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count