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A bacterial artificial chromosome (BAC RP23-461J2) that held the mouse Cbln2 gene was modified so that it expressed tamoxifen-dependent cre recombinase under the regulation of the mouse Cbln2 promoter. This modified BAC was microinjected into the pronucleus of a C57BL/6J zygote and randomly integrated into the genome of the mouse. The endogenous Cbln2 gene was not perturbed. (J:94077)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
