Bacterial artificial chromosome (BAC RP23-117B6) was modified to hold a cre recombinas under the control of the mouse Zic4 promoter. The cre recombinase possessed a poly-A tail to prevent expression of the Zic4 gene from the BAC. (J:94077)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count