An FRT site, IRES-beta-gal, loxP site, neo cassette, FRT site and loxP site were inserted in intron 1 and a loxP site was inserted in intron 3 via homologous recombination using the EUCOMM targeting vector HTGR06009_A_2_G03. Flp mediated recombination removed the beta-gal and neo cassettes leaving exons 2 and 3 floxed. (J:256610)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count