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A PGK-driven neomycin resistance gene flanked by FRT sites and followed by a loxP site were inserted 200 bp before exon 8 and another loxP site was inserted 200 bp after exon 9. Germline Cre-mediated recombination removed exons 8 and 9 and this is predicted to cause a frame shift resulting in a protein truncated at amino acid 405. (J:237108)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
