Frameshift mutations (1-nucleotide and 4-nucleotide deletions) were introduced in exon 1 using TALEN technology. TALEN RNAs were injected into the cytoplasm of pronuclear-stage oocytes. These alleles were found in mosaic form in Mutant 3. (J:244443)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count