An Y137A mutation was introduced in exon 3 and an FRT flanked pgk-hygro cassette was inserted in intron 2 via homologous recombination. Flp-mediated recombination removed the hygro cassette. RT-PCR indicates expression is initiated but not maintained in embryos. (J:257034)
Basic Information
(129S6/SvEvTac x C57BL/6NCrl)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count