Exons 2 to 4 were flanked by loxP sites and a FRT-flanked neomycin resistance gene was inserted abutting the loxP site in the intron found at the 3' end of exon 2. Flp-mediated recombination removed the neomycin cassette. (J:244472)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count