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EN
Exon 3b was replaced with on in which nulceotide substitutions result in the amino acid substitutions of alanine for 01 serine or threonine: T354A (ACT to GCC), S355A (TCC to GCC), S356A (TCC to GCC); T357A (ACA to GCA); S363A (TCT to GCC); T370A (ACT to GCC); S375A (TCC to GCC); T376A (ACG to GCC); T379A (ACA to GCA); T383A ( ACT to GCC). Cre-mediated removed a floxed neomycin resistance cassette inserted downstream of the modified exon 3b.
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
