A loxP site was inserted upstream of exon 3 and an FRT flanked neomycin resistance gene cassette and loxP site were inserted downstream of exon 3. Flpe-mediated recombination removed the neomycin cassette. (J:234504)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count