A loxP site was inserted upstream of exon 1. An FRT- and loxP-flanked neo cassette was inserted downstream of exon 1. Flp-mediated recombination removed the neo cassette. (J:256718)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count