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The targeting vector was generated by inserting IRES-Cre-FRT-flanked PGK-Neo into BAC RP23-108P5 clone containing mouse Mgp DNA fragment of 8.3 kb following endogenous stop codon. Targeted construct was introduced into ES cells to generate chimera founders. Resulting positive offspring were crossed with a flp deleter line to excise the neomycin resistance gene. (J:230973)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
