Exon 2 was flanked by two loxP sites and a neo cassette flanked by two FRT sites was inserted after the first loxP site. Flpe-mediated recombination removed the neo cassette leaving exon 2 floxed. (J:219058)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count