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The modified reverse tetracycline transactivator (rtTA) with an increased doxycycline sensitivity and lower basal activity (rtTA2S-M2) is expressed under the control of the rat myosin light chain 1 gene promoter and MLC1/3 enhancer. Expression is seen in skeletal muscle. Two lines were generated, with one studied further. (J:106884)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
