The coding sequences for an an internal ribosomal entry site (IRES) followed by an optimized FLP recombinase and a self-excising lox2372-flanked neomycin-Ace-cre cassette are introduced immediately after the Stop codon. In situ characterization demonstrates that flpo and Crh expression completely overlap in the pontine micturition center (PMC) in the pons. (J:101977)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129S6/SvEvTac x C57BL/6J)F1
Targeted
Insertion
--
1
1
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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