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Clone HTGRS6006_A_G10 from the BACPAC Resources Center, Knockout Mouse Project KOMP repository was used to target embryonic stem cells. The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. The first loxP site is followed by a neomycin under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of the targeted exon 3. Exon 3 is thus flanked by loxP sites. A conditional ready (floxed) allele is created by flp recombinase expression in mice carrying this allele. (J:238496)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
