LoxP sites were inserted 5' to exon 2 and 3' to exon 3. An Frt-flanked neomycin selection cassette was also inserted downstream of exon 3, but was removed via FLP-mediated recombination. (J:193194)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count