LoxP sites were inserted on both 5' and 3; of exon 2, which encodes the first zinc finger of the binding domain of the encoded protein. An adjacent frt-flanked neomycin selection cassette was removed by FLP1-mediated recombination. (J:256122)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count