The targeting vector contains a CAG (CMV-IE enhancer/chicken, beta-actin/rabbit-globin hybrid promoter), an FRT site, a loxP-flanked STOP cassette, a FLAG-tagged EGFP reporter gene fused to the channelrhodopsin-2 from the green alga Chlamydomonas reinhardtii modified to contain a E123A substitution (COP4*E123A), a woodchuck hepatitis virus post-transcriptional regulatory element (WPRE; to enhance the mRNA transcript stability), a poly-A signal, and an attB/att-flanked PGK-FRT-Neo-poly-A cassette. (J:236450)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
Targeted
Insertion
--
--
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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