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The targeting vector contains a loxP site flanked PGK-neo cassette, a mutant mouse Yap1 gene (with an amino acid substitution of serine-to-alanine at position 112), viral 2A peptide sequence, HIST1H2BJ/GFP (H2B-GFP) cDNA, beta-globin and polyadenylation sequence, under the control of the tetO, tetracycline-responsive regulatory element (TRE-tight). (J:255620)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
