Prkdc^M8Btlr

ENU-induced A to G transition at base pair 15,654,817 (v38) on chromosome 16, or base pair 17,364 in the GenBank genomic region NC_000082 within the splice acceptor site on intron 8. The effect of the mutation at the cDNA and protein levels have not examined, but the mutation is predicted to result in the use of a cryptic splice site in intron 8. The resulting transcript would have a 3-base pair insertion of intron 8, leading to an in-frame protein product beginning after amino acid 259 in encoded protein, which is normally 4,128 amino acids long. (J:255224)