The loxP sites were inserted flanking both extremes of exon 2 of the endogenous Tbx18 gene, encoding part of the DNA-binding domain critical for TBX18 activity. (J:253913)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count