A loxP site and an frt-flanked neomycin selection cassette were inserted 5' to exon 6 and a single loxP site was inserted 3' to exon 6. The neomycin selection cassette was removed in the germline via Flp recombination in the final conditional allele, leaving loxP sites flanking exon 6. (J:229307)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6
Targeted
Insertion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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