An FRT-flanked neomycin selection cassette and a loxP site was inserted downstream of exon 6 of the targeted gene another loxP site was inserted upstream of exon 6. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exon 6 floxed. (J:235023)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count