CRISPR/Cas9 mediated mutatgenesis was used to replace most of exon 2 (including the start codon) with an mTurquoise2 (green fluorescent protein in far blue) coding sequence and a loxP-flanked neomycin resistance (neo) cassette. Reporter expression is under the control of endogenous gene promoter. (J:252680)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6J x CBA/J)F1 x C57BL/6JIcoCrlLumc
Endonuclease-mediated
Insertion, Intragenic deletion
--
1
4
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Comparison
Al agent
Tutorials
Back to top