This allele was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences ACATCAATCAGAAAGGCCAG, TCCTGTCCACACATACCATA, AAAACGGTAAGACAGTGCCG and TATATTACTAGAGCTCAGGG, which resulted in a 709 bp deletion beginning at Chromosome 1 negative strand position 167,237,777 bp and ending after 167,237,069 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000160510 (exon 2) and 549 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 33 and early truncation 51 amino acids later. (J:188991)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count