LoxP sites were inserted to flank exon 2, which includes part of the 5' UTR and codes for the N-terminal 280 of 2542 amino acids of the protein. An adjacent FRT site flanked neomycin selection cassette was removed via Flp-mediated recombination in mice. (J:251454)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count