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A 9.4 kb portion of the upstream regulatory sequence for human S100B was inserted upstream of the coding sequence for the reverse tetracycline transactivator (rtTA) and human growth hormone polyadenylation sequences. This construct was used to create transgenic mice. Five founders were generated but only one gave robust expression in Schwann cells. The other four lines were discarded. (J:109980)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
