The transgene consists of the chicken beta-actin promoter and the CMV immediate-early enhancer, a loxP flanked STOP cassette, and the full-length mouse Bmp4 cDNA followed by an Ires-EGFP sequences. Excision of the STOP cassette by cre recombinase permits expression of Bmp4. Five lines were generated: 1, 2, 3, 4, and 5. (J:214763)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
--
Insertion
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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