A lox5171 site was inserted upstream of exon 1. An F3 site flanked hygromycin resistance cassette with a 5' lox5171 site was inserted downstream of exon 3. The construct was injected into ES cells containing the Tex19.1tm2Ics allele. Flp-mediated recombination removed the hygro cassette and left exons 1-3 floxed. (J:243444)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count