The transgene consists of the cytomegalovirus early enhancer/chicken beta-actin promoter, a loxP flanked chloramphenicol acetyltransferase (cat) gene followed by cDNA encoding HA-tagged mouse calreticulin. Cre mediated recombination results in excision of the cat gene and subsequent production of calreticulin. (J:199413)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count