A 1089-bp DNA fragment between nucleotides 25,289,972-25,291,060 on Chromosome 2 (Genome Build 38) containing the entire protein coding sequence was replaced by the ZEN-UB1 cassette, which contains the E. coli galactosidase gene (lacZ) and a loxP-flanked sequence comprising the promoter of the human ubiquitin C gene driving expression of neomycin phosphotransferase. The present allele was generated by Cre recombinase-mediated excision of the selection cassette. (J:136110)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NTac
Targeted
Insertion, Intragenic deletion
--
1
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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