This allele was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences TTACAACTCAGCTCTAAATG, CAGGGCCCATCGAGTTCCCA, TTATGACTAGAAGGCCACTG and ACTGTAACAAAACCACAGGA, which resulted in a 388 bp deletion beginning at Chromosome 10 negative strand position 39,895,021 bp and ending after 39,894,634 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001308224 (exon 2) and 219 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 7 and early truncation 21 amino acids later. (J:188991)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count