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The transgene insert comprises the following: 5.4 kb of genomic sequence containing the mouse myosin heavy chain alpha (cardiac) promoter and exons 1-3, a cDNA for the gamma1 isoform of the mouse Pparg gene and poly(A) features. This allele drives overexpression of the inserted gene in the heart, as shown by RT-PCR experiments. Two lines were used for furher study: a high expressing line and a low expressing line. (J:127393)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
