The targeting vector contains an FRT-flanked PuroR selection cassette inserted into intron 2 and an S65A point mutation inserted into exon 3. Flp-mediated recombination removed the FRT-flanked PuroR cassette. (J:341592)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count