The targeting vector contains loxP sites flanking exons 1 and 2 and a neomycin selection cassette. Germline cre-mediated recombination removed exons 1 and 2 and the neo cassette. (J:213546)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count