The transgene construct contains a Phage VII (Ph7/IRE) segment of DNA (derived from a regulatory region approximately 17.9 kb clone downstream of the Bmp5 coding sequences), and an Hsp68 (Hspa1b) minimal promoter-lacZ-SV40-pA reporter cassette. During embryonic development (E15.5 dpc), the transgene is expressed in several sites including the tips of the developing nasal turbinates and the thyroid cartilage. In adults, the transgene is expressed in multiple tissues following injury, including bone, skin and lung. (J:101977)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x DBA/2)F1
--
Insertion
--
--
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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