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The transgene contains a single base deletion that causes a frameshift and results in expression of a polypeptide containing the N-terminal signal sequence plus amino acids 1-237 of PR8 hemagglutinin (HA) driven by the SV40 early region promoter-enhancer and polyadenylation sequences. Two lineages were established, HA28 and HA37, with two to three transgene copies each. (J:137514)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
