A conditional human CAMK2G (isoform 3) over-expression cassette containing a T-to-D mutation at Thr287 (T287D) and a loxP-flanked STOP and a frt-flanked IRES-EGFP under the control of the CAG promoter was inserted into the locus. The T287D mutation allows for constitutive activation of the gene. (J:243363)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count